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    Home » Recipes » Entree

    Baked Spaghetti Casserole-Southern Recipe

    Modified: Aug 5, 2026 · Published: Sep 15, 2022 by Katie Crenshaw · 30 Comments

    This Southern baked spaghetti recipe is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added in. The trio combination along with a HOMEMADE meat sauce creates an incredibly wicked good, cheesy spaghetti dish. Once you have tried my Southern Baked Spaghetti Recipe once, it will be a favorite choice to make again and again! #bakedspaghetti #spaghetticasserole #spaghetti
    This will be the best #BakedSpaghetti Recipe you will ever make. Why Southern? There is no Mozzarella like the traditional Italian versions. Instead, I add in layers of Monterey Jack Cheese, Cheddar Cheese, and Pepperoni.
    This Southern baked spaghetti casserole is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added. The trio combination along with a HOMEMADE meat sauce creates an incredibly wicked good, cheesy pasta dish.
    This Southern baked spaghetti casserole is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added. The trio combination along with a HOMEMADE meat sauce creates an incredibly wicked good, cheesy pasta dish.
    This Southern baked spaghetti casserole is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added. The trio combination along with a HOMEMADE meat sauce creates an incredibly wicked good, cheesy pasta dish.
    This will be the best Baked Spaghetti Recipe you will ever make. Why Southern? There is no Mozzarella like the traditional Italian versions. Instead, I add in layers of Monterey Jack Cheese, Cheddar Cheese, and Pepperoni. The trio combination along with my HOMEMADE meat sauce creates an incredibly wicked good, cheesy spaghetti dish. Once you have tried my Southern Baked Spaghetti Recipe once, it will be a favorite choice to make again and again!
    ↓ Jump to Recipe

    This Southern baked spaghetti casserole is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added. The trio combination, along with a HOMEMADE meat sauce creates an incredibly wicked good, cheesy pasta dish.

    Spatula lifting a square of Southern baked spaghetti out of a baking dish.

    "I tried this recipe and it is sooo good. It has now become my favorite baked spaghetti!!"

    ★★★★★- April

    Jump to:
    • 🔍 Quick Look: Baked Spaghetti Recipe
    • A Note from my Kitchen
    • Ingredient notes and substitutions
    • Steps to make baked spaghetti casserole
    • Watch how to make
    • Cooking Tips
    • Meat Sauce Tips
    • Can you freeze spaghetti?
    • 📖 Recipe
    • 💬 Comments

    🔍 Quick Look: Baked Spaghetti Recipe

    ⏱️ Prep Time: 20 minutes
    ⏲️ Cook Time: 2 hours 20 minutes
    👥 Servings: 10
    📊 Calories: 686 per serving
    🍝 Main Ingredients: Ground beef, spaghetti, homemade meat sauce, Monterey Jack cheese, cheddar cheese, pepperoni
    ❄️ Make Ahead: Yes
    ⭐ Difficulty: Easy
    ❤️ You Will Love: Homemade meat sauce, gooey cheese, and pepperoni topping.

    A Note from my Kitchen

    They say, "It's all about the sauce." I say, "It is all about the sauce and the cheese!"

    I've been making this Southern baked spaghetti casserole for years, tweaking the recipe until it became just right. The rich homemade meat sauce, layers of gooey Monterey Jack and cheddar cheese, and crispy pepperoni topping come together to create the ultimate comfort food.

    I like to serve it with a warm loaf of garlic bread, a crisp Italian salad tossed with my Copy Cat Olive Garden Salad dressing, and a tall glass of Southern sweet tea. For dessert, my easy Southern banana pudding or Chocolate Cherry Sheet Cake is the perfect finishing touch.

    This is the kind of hearty, homemade meal that brings everyone to the table and always has people coming back for seconds. I hope your family enjoys it as much as mine does. Xoxo -Katie.

    baked spaghetti casserole ingredients-tomato sauce, diced tomatoes, ground beef, spaghetti, garlic, pepperoni, salt, oregano, celery salt, pepper, brown sugar, Italian seasoning, onion, bell pepper, Monterey Jack cheese, cheddar cheese

    Ingredient notes and substitutions

    You will need the following ingredients to make this homemade baked spaghetti:

    • canned diced tomatoes
    • tomato sauce- I recommend plain tomato sauce without the Italian seasoning because you'll season the sauce yourself.
    • ground beef- 85/15 or 90/10 blend works best. You can substitute with ground chicken or ground turkey.
    • Monterrey Jack cheese-freshly grated
    • garlic-garlic powder or crushed garlic
    • salt
    • pepperoni- Regular pepperoni or turkey pepperoni work great for this casserole.
    • spaghetti- You can substitute with angle hair pasta. My husband prefers the angle hair pasta, and I prefer the traditional spaghetti noodles.
    • black pepper
    • bell pepper- I recommend green bell pepper, but you can substitute with yellow or red bell pepper.
    • brown sugar- Balances the acidity of tomatoes without making the sauce sweet.
    • onion-You can substitute with onion powder.
    • cheddar cheese- Freshly shredded cheese melts better than the pre-shedded packages.
    • basil-fresh or dried
    • celery salt- or celery seasoning
    • Italian seasoning
    • oregano-fresh or dried

    *Full recipe with complete ingredient measurements are in the recipe card at the end of the post.

    teps to make baked spaghetti casserole

    Steps to make baked spaghetti casserole

    Follow easy steps on how to make baked spaghetti casserole:

    1. In a large stock pot, cook tomatoes, tomato sauce, onion, bell pepper, garlic, basil, Italian seasoning, oregano, celery salt, salt, pepper, and brown sugar at medium heat and bring to a boil.
    2. Cover, then reduce heat, and simmer for 30 minutes.
    3. In a separate skillet, crumble and cook ground beef.
    4. Add ground beef and water to stock pot, and cook an additional 30 minutes.
    5. Preheat oven to 350 degrees. Cook pasta noodles according to directions.
    6. In large 13x9 in pan lightly cover pan with meat sauce. About a ½ cup.
    7. Add ½ pasta noodles. Layer half of meat sauce. Layer remaining meat sauce.
    8. Layer Monterey Jack cheese. 
    9. Layer remaining pasta noodles. Layer remaining meat sauce.
    10. Layer Cheddar Cheese. 
    11. Finish with a layer of pepperoni, because why not? Pepperoni really makes this dish WICKED GOOD!
    12. Bake 30 minutes until cheese is completely melted and pepperoni is crispy.

    Watch how to make

    Cooking Tips

    • Simmering the sauce develops deeper flavor.
    • Don't over cook the pasta because it continues cooking in the oven.
    • Let the spaghetti casserole rest for 10-15 minutes before slicing.
    • Fresh shredded cheese melts better.
    • Cover with foil if the pepperoni browns too quickly.
    a serving of Southern Baked Spaghetti on a plate

    Meat Sauce Tips

    • I add the homemade sauce to the bottom of the 13x9 baking pan before adding the pasta. This keeps the pasta from sticking to the pan and drying out. 
    • Don't cut corners and buy premade jar sauce. It isn't the same and it won't be as good. I promise it is worth the effort to make your own sauce.
    A pan of baked spaghetti casserole with a metal spatula propped out of the side

    Can you freeze spaghetti?

    You can easily freeze spaghetti.

    The best way to freeze this spaghetti casserole recipe is to follow the instructions until it is time to bake in the oven. From there, cover it tightly with saran wrap and then a layer of tinfoil.This will protect it better from freezer burn. Thaw it out completely, then bake according to directions.

    If you have already baked it, you can freeze the leftovers in a freezer container, thaw, and reheat it when you are ready to eat.

    More tasty pasta dishes

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      Cheesy White Lasagna with Italian Sausage
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      Lazy Slow Cooker Ravioli Lasagna Recipe
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    • Chicken spaghetti casserole with green beans on a white serving plate.
      Cheesy Chicken Spaghetti Casserole Recipe

    Please leave me a comment below if you make this baked spaghetti and tell me what you thought about it. I would love to hear back, and so would my readers.

    Also post your picture of your spaghetti casserole on Instagram or Facebook, and tag @aforkstale with #aforkstale hashtags! I will share with my followers! xoxo!

    📖 Recipe

    baked spaghetti on a plate with a fork to the side

    Southern Baked Spaghetti Recipe- Spaghetti Casserole

    This Southern baked spaghetti casserole is unlike traditional Italian versions because there is no Mozzarella. Instead, layers of Monterey Jack cheese, cheddar cheese, and pepperoni are added. The trio combination, along with a homemade meat sauce creates an incredibly wicked good, cheesy pasta dish.
    4.95 from 50 votes
    Print Pin Save Recipe Saved! Rate
    Course: Main Course
    Cuisine: Southern
    Cook Time: 2 hours hours 20 minutes minutes
    Total Time: 2 hours hours 20 minutes minutes
    Servings: 10
    Calories: 686kcal
    Author: Katie Crenshaw

    Ingredients

    • 28 ounces can diced tomatoes
    • 28 ounces can tomato sauce
    • 1 small onion chopped
    • 1 bell pepper chopped
    • 2 garlic cloves crushed
    • ½ teaspoon basil
    • ½ teaspoon italian seasoning
    • ½ teaspoon oregano
    • ½ teaspoon celery salt
    • ½ teaspoon salt
    • 1 teaspoon pepper
    • 1 teaspoon brown sugar
    • ½ cup water
    • 2 pounds ground beef
    • 8 ounces cheddar cheese shredded
    • 8 ounces Monterey jack cheese, shredded
    • 8 ounces sliced pepperoni
    • 12 ounces box of spaghetti or angel hair pasta

    Instructions

    • In a large stock pot, cook tomatoes, tomato sauce, onion, bell pepper, garlic, basil, Italian seasoning, oregano, celery salt, salt, pepper, and brown sugar at medium heat and bring to a boil.
      28 ounces can diced tomatoes, 28 ounces can tomato sauce, 1 small onion, 1 bell pepper, 2 garlic cloves, ½ teaspoon basil, ½ teaspoon italian seasoning, ½ teaspoon oregano, ½ teaspoon celery salt, ½ teaspoon salt, 1 teaspoon pepper, 1 teaspoon brown sugar
    • Cover, reduce heat, and simmer for 30 minutes
    • In a separate skillet, crumble and cook ground beef.
      2 pounds ground beef
    • Add ground beef and water to tomato sauce, and cook an additional 30 minutes.
    • Preheat oven to 350 degrees. Cook spaghetti noodles according to directions. Do not overcook pasta because it continues to cook in the oven.
      12 ounces box of spaghetti or angel hair pasta
    • In large 13x9 in pan lightly cover pan with meat sauce. About a ½ cup.
    • Add ½ pasta noodles. Layer half of meat sauce.
    • Layer Monterey Jack cheese. 
      8 ounces Monterey jack cheese,
    • Layer remaining pasta noodles. Layer remaining meat sauce. Layer Cheddar Cheese. Cover cheese with pepperoni slices.
    • Layer Cheddar Cheese. 
      8 ounces cheddar cheese
    • Cover cheese with pepperoni slices.
      8 ounces sliced pepperoni
    • Bake in oven for 30 minutes or until cheese is melted and bubbly, and pepperoni is crispy.

    Video

    Notes

    *Cooking Tip: Whenever possible, use freshly grated cheese. It has more flavor and I swear it melts better.
    *Cooking Tip: My baked spaghetti recipe, adds layers of homemade sauce to the bottom of the 13x9 baking pan. This keeps the pasta from sticking. Don't cut corners and buy premade jar sauce. It isn't the same and it won't be as good. I promise it is worth the effort to make your own sauce.

    Nutrition- Nutrition info is based on estimation only.

    Calories: 686kcal | Carbohydrates: 35g | Protein: 38g | Fat: 43g | Saturated Fat: 19g | Cholesterol: 132mg | Sodium: 1488mg | Potassium: 873mg | Fiber: 3g | Sugar: 7g | Vitamin A: 880IU | Vitamin C: 23.7mg | Calcium: 402mg | Iron: 4.6mg
    Tried this recipe? I want to see it!Mention @aForksTale or tag #aForksTale!

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    Comments

      4.95 from 50 votes (24 ratings without comment)

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      Recipe Rating




    1. Marie Munday says

      June 04, 2023 at 10:06 pm

      I have leftover fettuccine. Can I use that instead of spaghetti? Thank you!

      Reply
      • Katie Crenshaw says

        June 04, 2023 at 11:06 pm

        Yes! It will just have a different texture, but I can't imagine it not being just as delicious.

        Reply
    2. Journa Liz Ramirez says

      September 28, 2022 at 4:50 am

      5 stars
      Never thought that it could be this good without mozzarella. I added this to my Holiday go-to recipe. My whole family loved it!

      Reply
    3. Lisa says

      September 26, 2022 at 12:41 pm

      5 stars
      Mmmmmnnn, so good! I love how the pepperoni gets slightly crispy on top.

      Reply
    4. Moop Brown says

      September 26, 2022 at 4:08 am

      5 stars
      Never would've thought to make spaghetti into a casserole so I'm definitely gonna have to try this recipe. I like that it can be frozen for later too.

      Reply
    5. Adriana says

      September 25, 2022 at 6:58 pm

      5 stars
      What a lovely idea for feeding a crowd. Now that the holidays are to start having recipes like this is so helpful. Cannot wait to make it!

      Reply
    6. Ann says

      September 25, 2022 at 2:54 pm

      5 stars
      I love a delicious baked spaghetti recipe! They are great to make extras, and freeze. I plan on making your recipe tonight for dinner!

      Reply
    7. Laura Arteaga says

      September 25, 2022 at 2:23 pm

      5 stars
      Great recipe for the whole family. The step-by-step pictures helped us to follow the recipe easily. Thank you!

      Reply
    8. Lauren Michael Harris says

      September 25, 2022 at 11:07 am

      5 stars
      Someone made us a spaghetti casserole when we had our son and it was so good that I wanted to look for a similar recipe. This is it! Loved the flavor - will make again!!

      Reply
    9. Dennis says

      September 24, 2022 at 8:19 pm

      5 stars
      Nothing beats a good spaghetti casserole! it had been years since I had one and your recipe was every bit as good if not better than ones I remember from my time in the south

      Reply
    « Older Comments
    Katie Crenshaw-A Fork's Tale

    Hi, I'm Katie!

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